Cialis has a high efficiency, which not only improves erection but also helps patients to recover naturalness of sexual relations. This is a reliable, efficient, easy to use and safe drug, it restores normal sexual life at patients suffering from erectile dysfunction, delivering them from constant thoughts about treatment.
Popular Questions about Cialis
How does Cialis act? Is it a sexual stimulant?
No, this drug is NOT a stimulant. For successful result you need sexual excitement. Everything happens naturally. Generic Cialis works precisely when it is necessary, but not when there is no need.
This agent has positive effect on the following manifestations and consequences of erectile dysfunction:
- erection in general;
- ability to achieve erection sufficient for sexual intercourse;
- ability to maintain erection during sexual intercourse;
- satisfaction from sexual intercourse;
- positive emotions;
- satisfaction from good erection;
- confidence in ability to achieve and maintain erection;
- partner’s satisfaction with sexual intercourse.
How does Cialis work?
Cialis is an effective, reversible inhibitor selectively acting on phosphodiesterase-5 (PDE-5).
Central role in erection is played by penis cavernous bodies smooth muscle cells relaxation, which is locally triggered by acetylcholine and nitric oxide, and other physiological agents. Acetylcholine is produced by parasympathetic nervous system neurons, and nitrogen oxide is released by non-adrenergic non-cholinergic neurons and endothelial cells. Resulting effect – sympathetic nervous system stimulation state or alpha stimulation suppression, which causes contraction of smooth muscle cells. Guanosine monophosphate (cGMP) and PDE-5 play important role for normal erection. cGMP causes arteries expansion, causing blood flow to cavernous bodies.
Blood vessels in cavernous bodies are filled with blood, which causes decrease in blood outflow from penis and blood pressure gradient – erection appears. PDE-5 enzyme causes decrease in cGMP level and terminates erection.
Tadalafil inhibits PDE-5 action, thus delaying cGMP level decrease. As a result, cGMP level in cavernous bodies allows men with erectile dysfunction to have a normal erection.
How effective is Cialis?
The drug improves erectile function at most men suffering from impotence of any degree.
Can Cialis cure severe erectile dysfunction?
Yes. In clinical trials, 81% of patients taking the pills of 20 mg observed improved potency. The study included patients with varying degrees of erectile dysfunction, from mild to severe.
How fast and how long does Cialis work?
At some men, the drug shows its effect within 16 minutes. For most patients, it takes 30 minutes. But remember, without sexual stimulation effect will not occur. The drug action lasts for about 36 hours after ingestion.
Is Cialis harmful for the heart?
Sexual activity is a risk in presence of heart diseases, so it is strongly recommended to consult a doctor before using the drug.
How often can Cialis be taken?
Recommended dosage is 20 mg. Maximal recommended frequency of admission – once a day.
What are Cialis contraindications?
Main contraindications:
- combined nitrates reception at cardiac angina;
- hypersensitivity to drug components.
What doctor can prescribe this drug?
Physician of any specialty, but first and foremost, urologist, sexologist, andrologist, endocrinologist and cardiologist.
If Cialis is safe and effective, why not to sell it without prescription?
Yes, clinical trials have demonstrated the safety of this Canadian drug. However, there are some drug interactions, especially with nitrates used in treatment of heart diseases. Therefore it is very important that this remedy is prescribed by doctor, thoroughly familiar with patient’s medical history.
How does Cialis interact with other drugs?
During clinical trials an insignificant interaction with other drugs or its complete absence was found. However, exceptions to this rule are nitrates, which are mainly used in treatment of cardiac disease. Therefore, tadalafil is contraindicated to patients receiving treatment with nitrates. The danger is possible significant sharp decrease in blood pressure – hypotension.
Once again, we remind that patients taking any nitrates should not take this ED preparation. If a patient is taking Cialis while taking any medication based on nitrates or recreational drug containing nitrates, blood pressure may decrease to dangerous levels. Many medications prescribed for chest pain treatment, caused by heart diseases contain nitrates These drugs include nitroglycerine (sprays, ointments, patches or pastes, and fast-disintegrating pills) or isosorbide mononitrate and dinitrate (pills that are ingested, chewed or dissolved under tongue). Certain recreational drugs such as amyl nitrate or nitrite («poppers») also contain nitrates This list is far from complete so it is important to ask patient whether he takes nitrates or preparations containing them.
What are Cialis side effects?
Possible side effects:
- headaches, dizziness;
- hot flashes;
- dyspepsia;
- nasal congestion;
- vision disorders (rare).
The most commonly reported adverse reactions are headaches and dyspepsia (11% and 7%, respectively). Adverse effects, connected with taking this drug, usually light or moderate in severity, transient and disappear at continued treatment. Other common adverse effects include back pains, myalgia, nasal congestion and blood «flushes» to face. Rarely – eyelids edema, eye pains, conjunctiva hyperemia and dizziness.
Cialis can’t be taken by every man. Patients taking any form of organic nitrates should not take tadalafil or any other PDE-5 inhibitor. This combination can cause dangerous blood pressure decrease. If a patient while having sex complains on chest pains or other symptoms related to cardiac activity, he should immediately consult a doctor. In clinical trials, the most common sides effect were headaches, indigestion, back pains, muscle pains and hot flushes. Usually, side effects are mild or moderate, quickly disappear and their frequency decreases with continued use. During clinical studies, most men did not experience serious side effects that would lead to tadalafil withdrawal.
Does Cialis affect fertility?
This drug has no effect on fertility. However, in cases where erection violations impede fertility in couples of child-bearing age, tadalafil may be useful.
Is Cialis effective for women?
The medicine is not intended to address problems in sexual sphere at women.
Are there any age restrictions for using this drug?
Cialis is not indicated for people under 18 years old.
Is Cialis a natural or synthetic product?
Its active ingredient is Tadalafil, a synthetic substance.
What is Cialis pharmaceutical form?
This drug is available in packages of 1 pill and 4 pills of 20 mg.
Can Cialis help patients with diabetes?
Yes. In clinical trials, 68% of men with diabetes who were treated with this drug observed an improved erection.
Is there any restriction for food intake?
No. this remedy can be taken with or without food, so patient and his partner should not change their habits.
Can Cialis be used on daily basis for a long time?
Everyday medication use is strongly undesirable.
Will patients experience erection if they do not want to?
No, sexual stimulation is required for the drug effectiveness.
Will this drug work if you take only half a pill?
The drug is designed at a dosage of 20 mg, it is not recommended to divide pills into smaller doses.
Who produces Cialis and is there analogs?
The drug is designed and produced by the well-known pharmaceutical company Eli Lilly (USA). Currently, other pharmaceutical companies are producing a cheaper and equally effective generic Cialis. Generic drugs are absolutely identical in composition, manufactured under other brands or under the name of active ingredient – tadalafil – and are much cheaper.